Salmon DNA
Polynucleotides Face Skin Booster

Our Salmon DNA polynucleotides (PN) face skin booster is an injectable biostimulator that improves hydration, firmness and skin texture without adding volume. Polynucleotide (PDRN) fragments from purified salmon DNA support natural repair, helping skin look smoother and more elastic. It is ideal for dullness, fine lines, crepey under‑eyes and uneven tone. At Evolution Aesthetics, we offer Salmon DNA Premium, Plinest Fast and Skin Booster (biorevitalisation) Plinest Gel to match different skin needs. Sessions are quick, downtime is minimal and results build over a few weeks. This treatment fits well into a long‑term skin quality plan and pairs with other skin procedures.
Stronger skin structure, deep hydration and low downtime gains
Deep hydration and glow from within
Polynucleotides bind water and improve the skin’s ground substance, giving a healthier, more hydrated look.
Results that build and last for months
PN (PDRN) stimulates fibroblasts for ongoing collagen and elastin renewal, so texture and firmness improve progressively.
Quick sessions, minimal interruption
Most appointments take 30–45 minutes with little downtime, so you can return to routine quickly.
Comfort‑first approach
Topical numbing and fine needles help keep treatment feel manageable for most people.
Precise placement, even under‑eyes
Microinjections allow accurate delivery to delicate zones such as the periorbital area.
Natural look without extra volume
This is a biostimulator, not a filler—skin quality improves without adding bulk.
Before and after

2 sessions

1 session

2 sessions

1 session
Biostimulation from salmon DNA polynucleotides rebuilds skin from within
Polynucleotides (PN), also known as PDRN, are long chains of DNA fragments purified from salmon sources to be biocompatible with human skin. When microinjected into the superficial dermis, these negatively charged molecules attract and hold water, improving tissue hydration and the gel‑like ground substance of the skin. PN also supports cellular repair by providing nucleotides for metabolism and by activating pathways (including adenosine A2A receptor signaling) that encourage fibroblast growth, collagen I/III synthesis and balanced inflammation. Over several weeks, this biostimulation enhances elasticity, smooths fine lines and improves overall texture. At Evolution Aesthetics, we tailor the product choice and technique to your skin: Salmon DNA Premium for comprehensive face rejuvenation, Plinest Fast for quicker spread and delicate areas like under‑eyes, and Skin booster (biorevitalisation) Plinest Gel when stronger hydration and dermal support are desired. The procedure uses sterile, single‑use needles or a cannula, with topical anaesthetic to keep you comfortable.Contraindications
We will assess your medical history before treatment. Please inform us about all conditions, medications and any past reactions to injectables.
- Pregnancy or breastfeeding
- Allergy to fish/salmon or any component of the product
- Active skin infection, acne flare, cold sores (herpes) or open wounds at the treatment area
- Uncontrolled autoimmune disease or immunosuppression
- Blood clotting disorders or current use of strong anticoagulants (consult your doctor first)
- History of keloid or hypertrophic scarring (case‑by‑case assessment)
- Active cancer or undergoing chemotherapy/radiotherapy
- Recent aggressive procedures at the same site (e.g., deep peels, ablative lasers) within recommended intervals
- Isotretinoin use within the last 6–12 months (ask our clinician for guidance)

Visible improvement in 2–3 sessions with results that last months
Most clients start with 2–3 sessions of Salmon DNA polynucleotides, spaced 2–4 weeks apart, depending on skin condition and goals. After the initial build phase, maintenance is typically 1 session every 3–6 months to keep hydration, elasticity and texture gains. A standard appointment lasts about 30–45 minutes, including consultation, numbing and microinjections. Before treatment: avoid alcohol for 24 hours; pause non‑essential blood thinners (like aspirin/ibuprofen) for 48 hours if your GP agrees; stop retinoids and acids on the area for 3–5 days; arrive with clean skin and no active breakouts. After treatment: expect mild redness, small bumps or pinpoint bruising for 1–3 days; avoid makeup for 12–24 hours, heavy exercise, sauna and steam for 24–48 hours; sleep with head slightly elevated the first night; use gentle cleanser, fragrance‑free moisturiser and broad‑spectrum SPF; avoid retinoids/acids for 3–5 days and postpone other facial procedures until the skin settles. Results begin with better hydration and glow in the first couple of weeks, with firmer, smoother texture continuing to build over 6–8 weeks. We often tailor the formula choice—Salmon DNA Premium, Plinest Fast, or Skin booster (biorevitalisation) Plinest Gel—to the area (e.g., under‑eyes) and the level of hydration or structural support required.What goes well with Salmon DNA Polynucleotides Face Skin Booster?
- Hydrafacial for Face or BackDo this 2–5 days before your booster to deep-clean pores, lift dead cells, and infuse hydration. A cleaner, well-hydrated canvas helps polynucleotides absorb more evenly and reduces the chance of post-treatment congestion for a clearer glow.
- RF Microneedling of FaceRF microneedling builds collagen structure; polynucleotides then support faster repair and smoother texture. Plan RF first and the booster about a week later to enhance firmness and fine-line softening.
- Clear Lift 4D Face Skin RemodelingThis non-ablative laser refreshes tone and targets early lines without raw skin. Pairing it with polynucleotides in the same treatment course amplifies elasticity and overall skin quality.
- Exosomes for FaceExosomes deliver cell-signaling cues that guide regeneration. Combined with polynucleotides—the building blocks for repair—you support both signaling and reconstruction, improving bounce and texture.
- LED TherapyRed and near-infrared LED after your booster calms redness and supports recovery. Better cellular energy and circulation help the polynucleotides work more effectively between sessions.
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