
Rejuran Results: Timing and Treatment Course
What Rejuran research can tell you about results, how to compare photographs and why treatment plans depend on the product and concern.
Evolution Aesthetics Clinic


Polynucleotide skin treatment
Rejuran Healer is a polynucleotide skin booster made with purified salmon-derived DNA fragments. Small injections may improve fine lines, rough texture and hydration as the response develops over several weeks. It is a skin-quality treatment, rather than a way to reshape your face.
At Evolution Clinic in Jumeira, Dubai, we offer Rejuran Healer 2 ml. Our doctor examines your skin and discusses what you want to change before recommending treatment.
key facts
Fine lines and uneven texture need a different approach from deep hollows or significant sagging.
We examine your skin, discuss previous treatments and explain the expected benefits, limitations and risks. Tell us about fish allergy, other allergies and any medicines you take.
If treatment is suitable, your doctor cleans the skin and places a series of small injections in the agreed areas. Injections can sting; we discuss suitable pain relief beforehand.
You may leave with visible raised points and redness. We give you written aftercare and arrange a review before deciding whether further sessions would help.
Questions
Rejuran is used to improve skin quality. It is not a substitute for a volumising filler when the concern is a deep hollow or loss of facial contour. Temporary swelling after injections is not the final result. We assess whether your concern comes from texture, volume loss, muscle movement or loose skin before recommending an option.
Polynucleotide injections have been studied for fine lines and skin quality around the eyes. Dark circles can also come from pigmentation, visible vessels or a shadow cast by a hollow; one injectable cannot correct all these causes. We assess the cause first. Our listed treatment is Rejuran Healer, and we confirm the appropriate product and area during consultation.
Published studies have used several sessions, often spaced two to four weeks apart. That is a research pattern, not a fixed prescription for everyone. We agree the course after examining your skin and review how you respond before recommending further treatment.
Assess changes over weeks, once the initial swelling has settled. Studies have followed patients for several months, but they do not establish one reliable duration for everyone. Skin condition, treatment area and the course affect the response. We compare your progress at review and discuss maintenance only if it is useful.
Raised injection points, redness, tenderness and swelling can remain visible after treatment; bruising can last longer. The manufacturer notes that local reactions may last about a week. Plan some recovery time before photographs or an important event. Contact us if a reaction worsens or does not settle, rather than assuming every lump is normal.
Tell us before booking. Rejuran contains purified salmon-derived material, so a history of fish allergy needs careful review. Purification does not justify a promise of no allergic reaction. A known allergy to an ingredient rules out that product; our doctor will discuss an alternative when appropriate.
Our licensed doctors assess your skin, explain the options and provide treatment within their approved scope and clinical privileges.

Specialist Dermatologist
Medical Director of Evolution Clinic, Specialist Dermatologist from Russia, M.D., Official Trainer for Laser Technologies. DHA License 03624607-001
Meet Yulia
General Practitioner
General Practitioner at Evolution Aesthetics Clinic in Dubai. DHA License 39929792-001.
Meet VeraTell us which area concerns you and whether you have had skin boosters before. Message us on WhatsApp or call to arrange a consultation.
Polynucleotides, or PN, are chains of DNA building blocks. Rejuran uses purified salmon-derived material in an injectable gel. The terms “salmon DNA treatment” and “skin booster” describe this treatment in everyday language; they do not mean it contains living cells.
A small randomised study of 27 people compared polynucleotides with non-crosslinked hyaluronic acid around the eyes. Both groups improved on appearance ratings, without a significant difference between them. Some measured changes in hydration, elasticity and roughness favoured PN. This supports discussing a possible skin-quality benefit, not promising rejuvenation or saying Rejuran is better for everyone.
Fine lines and surface roughness are different from deep creases, active acne or tethered acne scars. A smoother-looking surface does not mean pores have disappeared or a scar has been removed.
Small studies of polynucleotides for acne scars are encouraging, but products and techniques differ. Results for another PN formulation cannot automatically be applied to Rejuran Healer. We examine the scar pattern and active breakouts before discussing whether an injectable belongs in a wider treatment plan.
Fine, crepey skin, pigmentation, puffiness and a hollow can all make the eye area look tired. We assess them separately. Improving skin texture does not remove an eye bag or necessarily correct the shadow below it. The area needs careful product selection and injection technique.
Rejuran is a product family. Healer, i, S and HB formulations should not be treated as interchangeable names. This page covers the Rejuran Healer service we offer; we confirm the exact product before you consent.
PN and hyaluronic acid are different materials. Hyaluronic acid binds water; injectable formulations vary in how they are used for hydration or volume. Choosing between treatments means comparing the exact products, your skin concern, the evidence and the risks—not assuming every “skin booster” does the same job.
Volumising fillers address selected hollows or contours. Rejuran is considered for skin quality. More injections are not automatically a better plan; sometimes skin care or a different treatment is more appropriate.
Tell us about all previous injectables, including the product, area and date, as well as lasers, peels or other recent treatments. Bring a list of medicines and supplements. Do not stop prescribed treatment to prepare for a cosmetic appointment.
Let us know if you have an event or travel planned. We can discuss whether there is enough time for treatment and review, but cannot promise that marks will be gone by a particular day.
Follow the written instructions we give you for the product and treated area. The manufacturer advises avoiding makeup for 12 hours and prolonged sun, UV, extreme cold or heat exposure for two weeks. Discuss swimming, exercise, facials and other treatments with your doctor before resuming them.
Keep follow-up arrangements even if the skin looks better early on. Tell us about new or persistent lumps, colour changes or increasing discomfort. Do not book another injectable to correct a reaction before it has been examined.
We review the skin after the early injection effects have settled. Tell us what has improved and what still concerns you. Further sessions depend on your response and suitability, rather than an automatic commitment to ongoing injections.
We do not offer cosmetic Rejuran treatment during pregnancy or breastfeeding, or inject through infected or inflamed skin. Known ingredient allergy rules out treatment. Tell us about autoimmune disease, immune-suppressing treatment, bleeding problems, blood thinners and recent or permanent fillers so we can assess contraindications.
Possible effects include pain, itching, redness, swelling, bruising, lumps and colour changes. Infection and allergic reactions can occur. Accidental injection into a blood vessel can damage tissue. A small study reporting no serious adverse events does not rule out uncommon complications.
Get urgent medical attention for severe or increasing pain, pale or dusky skin, or any change in vision after a facial injection. Breathing difficulty, throat swelling or collapse needs emergency help; do not wait for a routine WhatsApp reply.
Evolution Aesthetics Clinic holds DHA Polyclinic License 6000514. We use authentic products from official, authorized suppliers and follow applicable UAE requirements for sourcing, storage and use. Our doctors work within their licensed scope and clinical privileges.
We explain the product, expected benefits, alternatives and material risks before consent, and provide written aftercare and a route for follow-up. We are happy to show you the product paperwork. These care standards do not remove treatment risks or guarantee a result.
Questions
Tell us about any planned injections, laser sessions, peels or facials before treatment. We decide the sequence after examining your skin and reviewing the exact products. Recent fillers and irritated skin can change whether Rejuran is appropriate, so do not assume treatments can be combined on the same day.
One session cannot guarantee a visible improvement by an event date. Early swelling can also look like a result before it settles. Tell us the date at consultation so we can discuss recovery time and whether it makes more sense to wait.
A serum is applied to the skin surface; an injectable is placed into tissue by a doctor. Even when products share a brand name or mention DNA-derived ingredients, their formulations, delivery and evidence differ. We can discuss skin care if you prefer to avoid injections.
Related reading
Product instructions and clinical studies inform the benefits, limitations and safety information on this page.
Personalised consultation
A licensed clinician will review your goals, medical history, treatment options, expected results, and individual risks before you decide.
Umm Al Sheif Road 49, Dubai
Open every day · 9:00 to 21:00